Lymphatic development is controlled by many genes, which regulates various events including lymphatic endothelial cell functions, the formation of a well-organized mature lymphatic vasculature with smooth muscle cell coverage and valves. 从淋巴管内皮细胞发育成为成熟的带有正常平滑肌细胞覆盖和瓣膜的淋巴管系统是一个非常复杂的过程,受到各种不同基因的调控。